Anti-Microbial Resistance by Medical PDF

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ISBN-10: 3805593236

ISBN-13: 9783805593236

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Infections with Organisms Producing Extended-Spectrum β-Lactamase 31 46 Denman SJ, Burton JR: Fluid intake and urinary tract infection in the elderly. JAMA 1992;267:2245– 2249. 47 Shlaes DM, Lehman MH, Currie-McCumber CA, Kim CH, Floyd R: Prevalence of colonization with antibiotic resistant gram-negative bacilli in a nursing home care unit: the importance of cross-colonization as documented by plasmid analysis. Infect Control. 1986;7:538–545. 48 Muder RR, Brennen C, Drenning SD, Stout JE, Wagener MM: Multiply antibiotic-resistant gramnegative bacilli in a long-term-care facility: a casecontrol study of patient risk factors and prior antibiotic use.

Thus far in the United States, ESBL-producing E. coli tend to be health care associated rather than community acquired. Nursing homes may be particularly important as sources of ESBL-producing E. coli in the United States. In a point prevalence study on the skilled care floor of a Chicago nursing home, 46% of residents were colonized with ESBL-producing organisms (all E. coli) [10]. These patients had been in the nursing home, without intercurrent hospitalization, for a mean of more than 6 months.

8 Brigante G, Luzzaro F, Perilli M, et al: Evolution of CTX-M-type beta-lactamases in isolates of Escherichia coli infecting hospital and community patients. Int J Antimicrob Agents. 2005;25:157– 162. 9 Blomberg B, Jureen R, Manji KP, et al: High rate of fatal cases of pediatric septicemia caused by gramnegative bacteria with extended-spectrum beta-lactamases in Dar es Salaam, Tanzania. J Clin Microbiol 2005;43:745–749. 10 Wiener J, Quinn JP, Bradford PA, et al: Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes.

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Anti-Microbial Resistance by Medical


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